Holger Rune defeated Botic Van De Zandschulp 6-3, 7(7)-6(4), 7(7)-6(2) in the R128 of the US Open 2025.
Botic Van De Zandschulp and Holger Rune have met 2 times, with Holger Rune leading the head-to-head 2–0.
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