Jan-Lennard Struff defeated Holger Rune 7(7)-6(5), 2-6, 6-3, 4-6, 7-5 in the R64 of the US Open 2025.
Jan-Lennard Struff and Holger Rune have met 2 times, with Jan-Lennard Struff leading the head-to-head 2–0.
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