Lorenzo Musetti def. Alex De Minaur 6-4, 6-2 — Madrid Open 2025 R16

Lorenzo Musetti defeated Alex De Minaur 6-4, 6-2 in the R16 of the Madrid Open 2025.

Head-to-head

Alex De Minaur and Lorenzo Musetti have met 3 times, with Lorenzo Musetti leading the head-to-head 3–0.

• Monte Carlo 2025 Semifinal — Lorenzo Musetti won 1-6, 6-4, 7(7)-6(4)
• Monte Carlo Masters 2025 Semifinal — Lorenzo Musetti won 1-6, 6-4, 7(7)-6(4)