Karen Khachanov def. Reilly Opelka 7(7)-6(3), 7(7)-6(4) — Madrid Open 2025 R64

Karen Khachanov defeated Reilly Opelka 7(7)-6(3), 7(7)-6(4) in the R64 of the Madrid Open 2025.

Head-to-head

Karen Khachanov and Reilly Opelka have met 1 time, with Karen Khachanov leading the head-to-head 1–0.