A son of Mar del Plata of Galician descent, Francisco Comesaña came up the long way — through the Argentine clay grind. He first competed at ITF Futures events in 2017, playing solely on clay until 2020, then moved to Córdoba in 2021 and won his maiden Challenger title in 2022. Introduced to the game at age seven, he began training at the Edison Lawn Tennis club, owned by Horacio Zeballos' family. The dirt-court apprenticeship paid off: after winning the Challenger title at the Open de Oeiras, he reached the top 100 for the first time on 22 April 2024.
He's a right-hander built in the classic South American mold — a two-handed backhand, heavy-spin patience, and the legs to win wars of attrition. The clay numbers tell the story, though his serve has sharpened lately: he's serving 7.7 aces per match over the last 52 weeks, up from a career average of 5.1. Against the elite he remains a live underdog rather than a regular threat — he holds a 2–5 record against players ranked in the top 10 at the time they met.
The signature scalps came fast. His breakout arrived at 2024 Wimbledon, ranked 122, where he stunned then-world-No. 6 Andrey Rublev for his first ATP-level win, first major win, and first top-10 victory, reaching the third round. On his US Open debut he again reached the third round, upsetting 17th seed Ugo Humbert. Then the biggest one: at the 2025 Rio Open he made his first ATP quarterfinal, defeating No. 2 Alexander Zverev, his biggest career win. He peaked at a career-high No. 54 on 18 August 2025.
The current beat runs through Paris. In May 2026 he reached the third round of Roland-Garros — his best major result — beating seeded Luciano Darderi before losing to Matteo Berrettini in a fifth-set tiebreak after more than five hours. Ranked 89, he remains the seeds' least favorite Tuesday draw.